This research objective was to study the possibility of reducing the doses of the drugs currently used in cancer patients was conducted by Ana Rosa Ballesteros Branch, Department of Anatomy and Embryology, University of Granada, and directed by the Antonia teachers Aránega Jimenez, Jose Carlos Prados Salazar and Consolation Melguizo Alonso.
His work has shown that "it is possible to use gene therapy as an aid to chemotherapy, improving his record when it comes to attack cancer, reducing the dose of the agents employed and helping decrease the side effects that lead to patients .
According to Ana Rosa Branch, now chemotherapy, radiotherapy and surgery results have "limited" in advanced stages of cancer, and therefore considers it is urgent to find new therapies, and gene therapy has emerged as a potentially powerful therapeutic platform .
In this paper, the results suggest the possibility of reducing the concentrations of chemotherapeutic agents in current use. Thus, lung cancer, scientists achieved a 14 percent inhibition of tumor growth and reduced 100 times the dose of Paclitaxel agent when combined with gene E.
In the case of colon cancer, the results were similar. However, the most relevant data was found in the line of breast cancer, in which the dose of the chemotherapeutic agent, doxorubicin, were reduced by 100 times reaching up to 21 percent inhibition of tumor proliferation when combined with the Gene E.